Parametric Analysis of Factor 8 (F8) Hemophilia A

A K M Raquibul Bashar, Dr. Chris P. Tsokos

Abstract


: In this study, we are going to address some of the basic questions about the Factor 8 (F8), which is the reason behind hemophilia A. because hemophilia affects 1 in 5,000 male births. About 400 babies are born with hemophilia each year. The exact number of people living with hemophilia in the United States is not known. A CDC study conducted in six states in 1994 estimated that about 17,000 people had hemophilia at that time. Currently, the number of people with hemophilia in the United States is estimated to be about 20,000, based on expected births and deaths since 1994[1]. In the United States, most people with hemophilia are diagnosed at a very young age. Based on CDC data, the median age at diagnosis is 36 months for people with mild hemophilia, 8 months for those with moderate hemophilia, and 1 month for those with severe hemophilia. So, after this study, we will be able to answer some critical basic questions from a statistical point of view, such as-does the level of severity depends on the races of the individuals? Is there any type of dependency among the inhibitor history, race and mutation type of the individuals? What could be the distribution of the level of severity? Etc.

 

 


Keywords


Inhibitor, F8, Hemophilia A,

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References


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